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Basics of LC/MS (5968-2543E)
applicable method than GC/MS, LC/MS is suitable for the analysis of large, polar, ionic, thermally unstable and involatile compounds. Some of these compounds can be made amenable to GC/MS by derivatization, but LC/MS eliminates the need for time-consuming chemical modifications. This permits MS analysis of non-volatile, thermally labile, or …